Journal: bioRxiv

Article Title: Linear gain effect of theta-burst and 15 Hz rTMS on intra-cortically measured neuronal responses to oriented grating visual stimuli

doi: 10.1101/2020.03.09.983932

Figure Lengend Snippet: Average normalized action potentials firing rate and gBLM responses in cTBS, iTBS, and 15 Hz rTMS experiments. In all cases, normalization was done with respect to responses on the time point right before the application of TMS.

Article Snippet: Trains of rTMS pulses of biphasic waveforms were generated by a Magstim Rapid TMS stimulator (Magstim, Whitland Dyfed, UK) and administered to cortical area 18 through the coil.

Techniques:

Journal: bioRxiv

Article Title: Linear gain effect of theta-burst and 15 Hz rTMS on intra-cortically measured neuronal responses to oriented grating visual stimuli

doi: 10.1101/2020.03.09.983932

Figure Lengend Snippet: Linear gain effect of TMS: Post-Vs Pre TMS responses to oriented grating stimuli for cTBS, iTBS, and 15 Hz rTMS conditioning. Each plot presents the average spiking response recorded by tuned channels after the delivery of a particular rTMS conditioning paradigm with respect to average spiking response recorded during the sustained part of the response by the same tuned channels before the delivery of rTMS, for a specific experiment run. Averaging took place across the prolonged part of the response (200-1000 ms following the presentation of the stimulus) and over three consecutive trials, separately for each channel and orientation. Responses obtained 1.7, 6.8 and 18.7 minutes (portrayed by red, green and blue markers, respectively) after the delivery of the particular rTMS paradigm were compared to responses averaged over 1.7 minutes before TMS delivery. The colored scatter plots represent the relationship between post-TMS responses to the pre-TMS response. The corresponding colored lines for the scatter plots are the orthogonal regression lines. The black lines represent the lines with slope 1 and intercept 0 (unity slope lines).

Article Snippet: Trains of rTMS pulses of biphasic waveforms were generated by a Magstim Rapid TMS stimulator (Magstim, Whitland Dyfed, UK) and administered to cortical area 18 through the coil.

Techniques:

Journal: bioRxiv

Article Title: Linear gain effect of theta-burst and 15 Hz rTMS on intra-cortically measured neuronal responses to oriented grating visual stimuli

doi: 10.1101/2020.03.09.983932

Figure Lengend Snippet: Time courses of the slopes and y-intercepts of the orthogonal regression lines and correlation coefficients applied to the scatter plots. The slope and intercept time courses represent the time point by time point results of orthogonal regression of responses to oriented gratings relative to the baseline responses recorded pre-TMS, for cTBS, iTBS and 15 Hz rTMS. The error bars represent the standard errors of mean (N = 8 experiments).

Article Snippet: Trains of rTMS pulses of biphasic waveforms were generated by a Magstim Rapid TMS stimulator (Magstim, Whitland Dyfed, UK) and administered to cortical area 18 through the coil.

Techniques:

Journal: bioRxiv

Article Title: Linear gain effect of theta-burst and 15 Hz rTMS on intra-cortically measured neuronal responses to oriented grating visual stimuli

doi: 10.1101/2020.03.09.983932

Figure Lengend Snippet: The upper panels present time courses of preferred orientation of each tuned channel, from one experiment with cTBS, iTBS, and 15 Hz rTMS. The lower panels present cumulative distributions of the maximum deviation of the preferred orientations of all tuned channels across all experiments. The maximum deviation is computed relative to the preferred orientations right before TMS, i.e. time point 5). In black, the deviations recorded at the beginning of the experiment session (−6.8 to −8.5 minutes with respect to when TMS is applied, also denoted by the black arrows in the upper panels). In red, the deviations recorded following the administration of rTMS (6.8 to 8.5 minutes following rTMS, also denoted by the red arrows in the upper panels).

Article Snippet: Trains of rTMS pulses of biphasic waveforms were generated by a Magstim Rapid TMS stimulator (Magstim, Whitland Dyfed, UK) and administered to cortical area 18 through the coil.

Techniques:

Journal: bioRxiv

Article Title: Linear gain effect of theta-burst and 15 Hz rTMS on intra-cortically measured neuronal responses to oriented grating visual stimuli

doi: 10.1101/2020.03.09.983932

Figure Lengend Snippet: Average tuning curves of three trials right before (black) and right after (red) the administration of cTBS, iTBS, and 15 Hz rTMS. The darker lines represent the mean values whereas the lighter regions around them show the standard error of means across all experiments. The vertical solid black and dotted red lines mark the widths of the tuning curves at the corresponding half heights before and after TMS, respectively.

Article Snippet: Trains of rTMS pulses of biphasic waveforms were generated by a Magstim Rapid TMS stimulator (Magstim, Whitland Dyfed, UK) and administered to cortical area 18 through the coil.

Techniques:

Journal: bioRxiv

Article Title: Linear gain effect of theta-burst and 15 Hz rTMS on intra-cortically measured neuronal responses to oriented grating visual stimuli

doi: 10.1101/2020.03.09.983932

Figure Lengend Snippet: Time courses of the amplitude (response to preferred orientation minus the response to the orthogonal-to-preferred orientation, normalized to the same measure obtained just-prior to TMS), DC (response to the non-preferred orientation) half-width at half-maximum-height and circular variance of the fitted tuning curves. The left, middle and right columns present the values obtained from applying cTBS, iTBS, and 15 Hz rTMS, respectively.

Article Snippet: Trains of rTMS pulses of biphasic waveforms were generated by a Magstim Rapid TMS stimulator (Magstim, Whitland Dyfed, UK) and administered to cortical area 18 through the coil.

Techniques: